CoQ10 – Cellular energy – an inside job

In the quest for increased energy and vitality, many of us would prefer the simplicity of replacing our cellular batteries with new ones, much like replacing a traditional battery when our energy and vitality wanes. Our cellular energy is literally an inside job and is one of the most crucial functions of the human body carried out by the mitochondria which are the powerhouses of our cells. Our mitochondria small structures called organelles that create energy known as ATP (adenosine triphosphate) inside of our cells, as well as play a role in maintaining cell survival, cell death and metabolic homeostasis. 

Mitochondria must function around the clock as our cells cannot store ATP and are dependent on oxygen, water, carbohydrates, and nutrients to carry out this vital role. Some cells contain a few mitochondria whereas others can contain 1,000’s as some cells/organs are more energy-demanding such as the heart, brain, and liver.

At the heart of cellular energy production lies the Electron Transport Chain (ETC), an intricate mechanism within the mitochondrial membrane. This highly active process is dependent on vital nutrients, such as Coenzyme Q10 (CoQ10). The ETC, akin to a cellular pass-the-parcel game, transports high-energy electrons to produce ATP. 

Whilst acknowledging the importance of other nutrients, such as those from the B vitamin family and magnesium, CoQ10 emerges as a key player in this dynamic process, ensuring a seamless flow of energy.

What is CoQ10?

First discovered in 1940 and isolated from the mitochondria of beef heart, CoQ10 is vital for the electron transport chain and this compound is naturally produced within our cells, however, its production, unfortunately, diminishes as we get older.

Beyond being a vital participant in the electron transport chain, CoQ10 is a potent lipid- antioxidant safeguarding our important cellular membranes and contributing to the regeneration of well-known antioxidants like Vitamin C and E.

We can obtain varying amounts from our diet from food such as egg yolks; oily fish, organ meats, natto, nuts, seeds, and others. Less CoQ10 can also occur when we have high energy demands that are greater than our ability to produce enough; such as intensive exercise or under chronic stressful conditions.

Ageing is a major factor of CoQ10 deficiency as the levels start to diminish which puts us at risk of age-related diseases.

Ageing and CoQ10

Supporting mitochondria function and protecting our cells from oxidative damage is important to slow down the ageing process. Many signs point to possible low cellular levels of CoQ10 as the impairment of mitochondrial function; and reduced anti-oxidant activity can lead to oxidative stress which contributes to the ageing signs of: 

• Lowered energy
• Poor physical performance
• Inflammation
• Oxidative stress
• Neurodegenerative diseases
• Blood sugar imbalances
• Cancer
• Cardiovascular diseases

We also have the outward signs of ageing such as wrinkles and sagging skin; CoQ10 has been shown to reduce the appearance of these telltale signs which is why many anti-ageing creams contain CoQ10 as a popular ingredient. 

Taking CoQ10 as an oral supplement has also shown to be effective in reducing wrinkles; and improving skin smoothness, particularly around the eyes, mouth; and lips where those telltale signs of ageing and oxidative stress often reveal themselves. Over a 12-week period taking a dose of 150mg per day was associated with a reduction in wrinkles compared to a placebo

Premature ageing due to lifestyle such as smoking, poor diet, chronic stress; over-exercising can also lead to many symptoms of early ageing as our mitochondria are vulnerable to toxins; nutrient deficiencies and oxidative damage caused by lack of vital nutrients our cells need for energy production and antioxidant support.

Further ways we deplete CoQ10

Deficiencies in CoQ10 can occur for other reasons than just ageing, and inadequate dietary intake. Some medical drugs such as statins, a prescribed drug for high cholesterol and the treatment of cardiovascular disease; block the essential pathways that result in the production of CoQ10. This commonly leads to symptoms such as low energy and muscle pain. Metformin is another prescribed drug that is associated with CoQ10 depletion. 

Taking a supplemental CoQ10 is not only associated with improved energy and physical performance; it has shown promising results for many other health conditions such as:

• Periodontal disease
• Migraine prophylaxis
• PCOS (Polycystic ovary syndrome)
• Decreasing of pain, fatigue and morning tiredness associated with fibromyalgia
• Cardiovascular health
• Neurodegenerative diseases

Recognising drug-nutrient depletions is crucial and the need for supplementation to maintain optimal levels should not be ignored. 

Ways to support mitochondrial function

Ensuring adequate nutrient intake is vital, ensuring good levels of CoQ10 and where needed supplementing with CoQ10 and anti-oxidants can provide our mitochondria the power and the protection they need to function optimally.

There are many other ways to support mitochondrial function that we could incorporate into our lifestyle such as decreasing toxin exposure, healthy levels of exercise, improved sleep, healthy levels of sunlight and fresh air. Cold exposure, intermittent fasting, and more can also help mitochondrial function.

CoQ10 stands out as more than a mere facilitator of cellular energy, it is a guardian of vitality, defends us against oxidative stress, and helps us buffer the wear and tear of life, it emerges as a noteworthy defender against the natural ageing process. Visit Nutrilink.co.uk website for more information.